Welcome to Isaac Li's Research Group @ UBC Okanagan

We study the biophysics of cells at the single molecule and single cell levels. Our studies address fundamental cell biology questions that have many practical applications from smart DNA-based biomaterials to cell screening technology. Our research focuses on the following areas:

  • Techniques to manipulate individual molecules and cells
  • Nano-biotechnology of DNA-based smart biosensors, molecular motors and biomaterials
  • Mechano-biology at the single-molecule level
  • Cell screening technologies

Our research is highly interdisciplinary, we work at the interface of cell biology, physical chemistry, biophysics, nanotechnology, and engineering. Talents from all backgrounds are welcomed!





We are hosting the second Western Canada Biophysics Conference (WCBC) at UBC Okanagan on Saturday, Sept.14, 2019. All are welcome to attend

We just received the NFRF fund!

Congrats to Adam Yasunaga on getting NSERC CGS-M.

Summer and Alex's paper on exosome made APL bioengineering cover!
Yousif's serial TGT paper is highlighted by Biophys J.
Congrats to Alex and Victoria on getting NSERC USRA summer fellowship.
Congrats to Sydney on getting URA summer fellowship.

Positional paper on Minimal information for studies of extracellular vesicles standard (MISEV2018) is published in JEV with colleagues in the EV field.

Congrats to Adam on his first paper in collaboration with Susan Murch, now published in Journal of Pineal Research
Congrats to Adam on receiving the graduate travel award to BSC 2019 meeting in Toronto.
Eminence cluster with Dr. Soheil Mahmoud is funded!

Yousif successfully defended his MSc! My first MSc student!
Welcome Omkar to the lab, co-supervised with Fred Menard.

Yousif got into UBC's medical school program in Kelowna, Congratulations!
Keith got into U of T's graduate program in Chemistry, Congratulations!

Adam received a poster award in the URC conference, Congrats Adam!
Congratulations to Alexander Corbett, who received the NSERC-USRA to work in our lab this summer.
Welcome Dr. Yuechao Tang and Dr. Summer Li to join the lab as Eminence postdocs!

Congratulations to Sydney Fearnley, who received the URA award and will join the lab this summer!

Congratulations to Yousif Murad, who received the graduate travel award!

We receive funding to establish 2 Eminence research clusters at UBC Okanagan!

We received Mitacs Globalink support to host Zhongyi Dai this summer. Welcome to the lab Zhongyi!
Welcome Adam Yasunaga to the lab, and congratulations on getting the Undergraduate Research Award (URA)!

We are hosting the first Western Canada Biophysics Conference (WCBC) at UBC Okanagan on Wednesday, Mar. 15, 2017. All are welcome to attend
Our cell rotation tracking and molecular footprinting paper accepted to Sci Rep!

Welcome Sara Tasnim, the second MSc student to join the lab! And congratulations on receiving the GDES!

We received another work-study program funding!

We received the UBC Internal Research Fund!

We got infrastructure matching fund from BCKDF!
Welcome Nolan Frymire to join the lab.

Work-Study research opportunity open for 2016 Fall - Computational Modelling of Cancer Cell Adhesion in Microfluidics, application deadline Aug.31.

Welcome Yousif Murad, the first MSc student to join the lab.

Sophia Ng, Victor Sun, and Christine Furrer will join the lab for undergraduate thesis, welcome!
Cameron Inglis, Dawei Gu, Katya Plimley, and Sabrina Slade joins the lab for summer research, welcome!

We got funded by Canada Foundation for Innovation (CFI)!

Manuscript on single molecule tension sensor construction is published in Scientific Report!

Dr. Li joins Department of Chemistry at UBC Okanagan!

Our manuscript on how osmolyte influence hydrophobic interaction is published in PNAS!

Our manuscript on the role of single molecular force dictating integrin based cell spreading is published in Integrative Biology!