The course will provide detailed biophysical and biochemical characteristics of nucleic acid. The course will emphasize on the modelling of DNA’s biomechanics and structural transition using statistical mechanics method. In addition, the course will also discuss modern experimental techniques to study DNA as well as bio-nanotechnologies that use DNA as functional material.
Term 1 - Mon | Wed | Fri 11:30-12:30 am (ART103)
Mon 3:00-5:00 pm (FIP343)
Cellular and Molecular Biophysics (CHEM422X | BIOC420X | CHEM507X)
Biophysical principles behind molecular and cellular processes. Topics include: protein folding, DNA mechanics, molecular self-assembly, molecular motor, systems biology, cell motility, mechanobiology, cell sensing, biomolecular networks, and biological pattern formation. Tools and techniques used at the frontier of nanoscience and nano-bio-technology will be introduced including: molecular biosensors, aptamers, DNA-origami, single-molecule biophysics, super-resolution microscopy, and DNA sequencing.
Term 2 - Mon | Wed | Fri 10:30-11:30 am (ART210)
Tues 1:00-2:00 pm (FIP343)
Biophysical Chemistry Labs (CHEM305)
07 - Conductance and diffusion
10 - Introduction to self-assembly: micelle properties
15 - Molar mass determination by viscosity
17 - Electrophoresis of amino acids
19 - Determination of diffusion constant
22 - Myoglobin transitions
25 - Osmosis and permeability
26 - Thermodynamics of glycine
Modern Instrumentation for Single-Molecule Chemistry (CHEM568W)
This course will introduce a variety of modern techniques to study the physical chemistry of individual bio-macromolecules. In particular, single-molecule microscopy and optical manipulation techniques that probes the conformational dynamics and energy landscapes of proteins and DNAs, as well as their interactions will be discussed.
Please join us to learn about the biophysics, bioengineering, and chemical biology research. We have Dr. Nancy Forde from SFU as keynote guest speaker. Local speakers include: Dr. Mina Hoorfar, Dr. Andrew Jirasek, Dr. Frederic Menard, and myself. Click here for more detail.
Join us to learn about this year’s Nobel Prize-winning contributions in medicine, physics, chemistry, literature, economics and peace from distinguished UBC researchers. (Highlights)
About the Physics Prize - TBA
About the Chemistry Prize - Dr. Isaac Li,
About the Medicine Prize - Dr. Bruce Mathieson
About the Literature Prize - Dr. Oliver Lovesey
About the Peace Prize - Dr. Jessica Stites Mor
About the Economic Sciences - Dr. Ross Hickey
Isaac Li | FIPKE 343 | email@example.com | 250.807.8069
Department of Chemistry | University of British Columbia | Okanagan
3247 University Way, Kelowna, British Columbia, V1V 1V7, CANADA